Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593736 | 0.82 | TERT (0.55) | LMNAL3MBTL1CYP2A6MAPTKDM4E | |
| SCHEMBL3240233 | 0.80 | CYP2A6 (0.47) | L3MBTL1CYP2A6IGLV6-57ADRA2AADRA2B | |
| SCHEMBL29543329 | 0.79 | APP (0.50) | LMNAL3MBTL1CYP2A6NCEH1MAPT | |
| SCHEMBL645807 | 0.79 | APP (0.50) | LMNAL3MBTL1CYP2A6NCEH1MAPT | |
| SCHEMBL1433223 | 0.79 | ADRA2A (0.48) | L3MBTL1CYP2A6MAPTKDM4EMEN1 | |
| SCHEMBL17268809 | 0.78 | IGLV6-57 (0.47) | L3MBTL1MAPTKDM4EALDH1A1IGLV6-57 | |
| SCHEMBL4064736 | 0.76 | HTR7 (0.44) | LMNAALDH1A1MAPK1GAA | |
| SCHEMBL16682949 | 0.75 | ADRA2A (0.46) | L3MBTL1CYP2A6MAPTKDM4EMEN1 | |
| SCHEMBL31457375 | 0.74 | APP (0.48) | CYP2A6NCEH1MAPTKDM4EMEN1 | |
| SCHEMBL10330355 | 0.71 | ADRA2A (0.58) | L3MBTL1CYP2A6MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557811-B2 | Dual-color imaging method of sodium/calcium activities using two-photon fluorescent probes and preparation method of two-photon fluorescent probes | Ajou University Industry—Academic Cooperation Foundation (KR) | 2013-10-15 | — | — | US | disclosed |
| US-20120035360-A1 | DUAL-COLOR IMAGING METHOD OF SODIUM/CALCIUM ACTIVITIES USING TWO-PHOTON FLUORESCENT PROBES AND PREPARATION METHOD OF TWO-PHOTON FLUORESCENT PROBES | AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION | 2012-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035360-A1 | DUAL-COLOR IMAGING METHOD OF SODIUM/CALCIUM ACTIVITIES USING TWO-PHOTON FLUORESCENT PROBES AND PREPARATION METHOD OF TWO-PHOTON FLUORESCENT PROBES | CACNB2, CA2, ATP2A2 | LMNA 773/4885L3MBTL1 3676/4885CYP2A6 3082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.