Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281280 | 0.86 | PTGS2 (0.39) | KDM4EPTGS2 | |
| SCHEMBL14624155 | 0.84 | KDM4E (0.33) | KDM4EALDH1A1POLBPTGS2NPC1 | |
| SCHEMBL5288747 | 0.84 | PTGS2 (0.38) | L3MBTL1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5280436 | 0.78 | POLB (0.37) | L3MBTL1KDM4EALDH1A1POLBMEN1 | |
| SCHEMBL14624160 | 0.78 | HTT (0.35) | POLBPTGS2NPC1CYP2C9RAB9A | |
| SCHEMBL5296183 | 0.76 | POLB (0.34) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL5325697 | 0.75 | RAD51 (0.40) | PTGS2NPC1CYP2C9RAB9A | |
| SCHEMBL5331474 | 0.74 | PTGS2 (0.38) | KDM4EMEN1KMT2APTGS2MAPT | |
| SCHEMBL14622453 | 0.73 | CYP11B1 (0.43) | KDM4EALDH1A1POLBNPC1RAB9A | |
| SCHEMBL5294487 | 0.73 | POLB (0.39) | KDM4EALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |