Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14624155 | 0.87 | KDM4E (0.33) | PTGS2PTGS1KDM4E | |
| SCHEMBL5288747 | 0.87 | PTGS2 (0.38) | PTGS2PTGS1KDM4ECHRNA7 | |
| SCHEMBL5288324 | 0.86 | L3MBTL1 (0.36) | PTGS2KDM4E | |
| SCHEMBL5324677 | 0.81 | RGS4 (0.46) | PTGS2PTGS1 | |
| SCHEMBL5280436 | 0.79 | POLB (0.37) | PTGS2PTGS1KDM4E | |
| SCHEMBL14624160 | 0.79 | HTT (0.35) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5296183 | 0.77 | POLB (0.34) | PTGS2PTGS1KDM4E | |
| SCHEMBL5325697 | 0.75 | RAD51 (0.40) | PTGS2PTGS1CHRNA7 | |
| SCHEMBL5331474 | 0.74 | PTGS2 (0.38) | PTGS2PTGS1KDM4ECHRNA7 | |
| SCHEMBL14622453 | 0.74 | CYP11B1 (0.43) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |