Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292958 | 0.76 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL5288721 | 0.75 | POLB (0.41) | POLBKDM4EALDH1A1TDP1PTGS2 | |
| SCHEMBL5281280 | 0.74 | PTGS2 (0.39) | KDM4EPTGS2CHRNA7PTGS1 | |
| SCHEMBL14622407 | 0.74 | PTGS2 (0.38) | ALDH1A1PTGS2LMNAHTTCHRNA7 | |
| SCHEMBL5331474 | 0.73 | PTGS2 (0.38) | KDM4EPTGS2LMNAHTTCHRNA7 | |
| SCHEMBL5288324 | 0.73 | L3MBTL1 (0.36) | POLBKDM4EALDH1A1PTGS2NPC1 | |
| SCHEMBL5280436 | 0.73 | POLB (0.37) | POLBKDM4EALDH1A1TDP1PTGS2 | |
| SCHEMBL14624160 | 0.72 | HTT (0.35) | POLBPTGS2LMNAHTTCHRNA7 | |
| SCHEMBL5326545 | 0.72 | PTGS2 (0.39) | KDM4EALDH1A1PTGS2PKMLMNA | |
| SCHEMBL14624155 | 0.72 | KDM4E (0.33) | POLBKDM4EALDH1A1PTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |