Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281280 | 0.79 | PTGS2 (0.39) | KDM4EPTGS2PTGS1 | |
| SCHEMBL5288324 | 0.78 | L3MBTL1 (0.36) | POLBALDH1A1KDM4EPTGS2MAPT | |
| SCHEMBL5292958 | 0.77 | PTGS2 (0.56) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL5288721 | 0.76 | POLB (0.41) | POLBALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL14624160 | 0.73 | HTT (0.35) | POLBPTGS2PTGS1RAD51THRB | |
| SCHEMBL14624155 | 0.73 | KDM4E (0.33) | POLBALDH1A1KDM4ENPSR1PTGS2 | |
| SCHEMBL5294487 | 0.73 | POLB (0.39) | POLBALDH1A1KDM4ENPSR1PTGS2 | |
| SCHEMBL5296183 | 0.71 | POLB (0.34) | POLBALDH1A1KDM4EHPGDPTGS2 | |
| SCHEMBL5325697 | 0.70 | RAD51 (0.40) | PTGS2PTGS1RAD51THRBCYP2C9 | |
| SCHEMBL5331474 | 0.69 | PTGS2 (0.38) | KDM4EPTGS2PTGS1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |