Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MET | P08581 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328645 | 0.83 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MAPK1PPARDLMNA | |
| SCHEMBL5328644 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MAPK1LMNAMET | |
| SCHEMBL5291890 | 0.74 | PPARD (0.41) | SMN1; SMN2FFAR1PPARDLMNAMAOB | |
| SCHEMBL5298909 | 0.69 | POLB (0.45) | ALDH1A1HTTKMT2AMAPTTP53 | |
| SCHEMBL5298422 | 0.68 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2FFAR1KDM4EHTT | |
| SCHEMBL5297846 | 0.66 | AR (0.45) | SMN1; SMN2LMNAMAOBNPC1RAB9A | |
| SCHEMBL7535556 | 0.66 | TUBB1 (0.43) | ALDH1A1SMN1; SMN2MAPK1LMNANPC1 | |
| SCHEMBL29665700 | 0.66 | TUBB1 (0.43) | ALDH1A1SMN1; SMN2MAPK1LMNANPC1 | |
| SCHEMBL30745833 | 0.64 | LMNA (0.48) | ALDH1A1SMN1; SMN2MAPK1LMNAMAOB | |
| SCHEMBL5290581 | 0.64 | PLCG1 (0.47) | ALDH1A1SMN1; SMN2LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | claimed |