Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293270 | 0.78 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL5359842 | 0.77 | LMNA (0.33) | SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL5328645 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL5291890 | 0.71 | PPARD (0.41) | SMN1; SMN2LMNARAB9AMAOB | |
| SCHEMBL5298909 | 0.68 | POLB (0.45) | ALDH1A1MAPTTP53 | |
| SCHEMBL7535556 | 0.65 | TUBB1 (0.43) | SMN1; SMN2ALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL29665700 | 0.65 | TUBB1 (0.43) | SMN1; SMN2ALDH1A1MAPK1LMNANPC1 | |
| SCHEMBL30745833 | 0.63 | LMNA (0.48) | SMN1; SMN2ALDH1A1MAPK1LMNARAB9A | |
| SCHEMBL5298171 | 0.62 | TXNRD1 (0.45) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL24458142 | 0.62 | TUBB1 (0.39) | ALDH1A1MAPK1LMNARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007012724-A1 | 1,2,4-THIADIAZOLE DERIVATIVES ANTIFUNGAL COMPOUNDS, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | CYTOMICS SYSTEMS (FR) | 2007-02-01 | — | — | WO | disclosed |