Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | NPR3 | P17342 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5306751 | 0.88 | STK17B (0.37) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL5305779 | 0.86 | AAK1 (0.36) | ATRAAK1CA12CA1CA2 | |
| SCHEMBL5804885 | 0.85 | MEN1 (0.38) | AAK1CA12CA1CA2CA9 | |
| SCHEMBL5311129 | 0.84 | LMNA (0.34) | ATRAAK1ABCB1TRPA1 | |
| SCHEMBL8140939 | 0.79 | AAK1 (0.47) | ATRAAK1TRPA1STK17BSTK17A | |
| SCHEMBL5454475 | 0.73 | AAK1 (0.34) | AAK1TRPA1 | |
| SCHEMBL5306326 | 0.72 | STK17B (0.47) | ATRAAK1TRPA1STK17BSTK17A | |
| SCHEMBL5309237 | 0.72 | STK17B (0.40) | ATRAAK1TRPA1STK17BSTK17A | |
| SCHEMBL5791173 | 0.72 | GPR119 (0.39) | AAK1TRPA1 | |
| SCHEMBL5794142 | 0.71 | MEN1 (0.40) | ATRAAK1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |