Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791173 | 0.88 | GPR119 (0.39) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL5311129 | 0.88 | LMNA (0.34) | AAK1CTSLCTSBCTSSNSD2 | |
| SCHEMBL5305779 | 0.85 | AAK1 (0.36) | AAK1AR | |
| SCHEMBL5791037 | 0.82 | CTSK (0.42) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL8245020 | 0.77 | CTSL (0.43) | AAK1CTSLCTSBCTSSNSD2 | |
| SCHEMBL5791032 | 0.77 | GPR119 (0.40) | AAK1CTSLCTSBCTSSNSD2 | |
| SCHEMBL5819676 | 0.76 | CTSK (0.41) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL5306751 | 0.75 | STK17B (0.37) | AAK1TRPA1 | |
| SCHEMBL8268828 | 0.74 | CTSK (0.42) | AAK1CTSLCTSBCTSSCTSK | |
| SCHEMBL5302833 | 0.74 | CTSS (0.37) | AAK1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |