Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308285 | 0.91 | DRD2 (0.58) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5328407 | 0.90 | SLC6A4 (0.55) | SLC6A4ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL5302822 | 0.89 | ADRA1A (0.65) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5310370 | 0.86 | ADRA1A (0.50) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL6211876 | 0.84 | HTR1A (0.59) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5325863 | 0.80 | DRD2 (0.59) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5329403 | 0.80 | ADRA1A (0.65) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL6211262 | 0.77 | DRD2 (0.54) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5306802 | 0.76 | ADRA1A (0.49) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL5176069 | 0.75 | HTR1A (0.55) | ADRA1DADRA1AADRA1BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029156-A2 | ISOINDOLEDIONE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |