Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317773 | 0.82 | ASAH1 (0.40) | TDP1 | |
| SCHEMBL13754063 | 0.79 | ALDH1A1 (0.40) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5317035 | 0.74 | LMNA (0.33) | CYP3A4 | |
| SCHEMBL13754072 | 0.71 | HDAC7 (0.44) | CYP3A4CYP2C19 | |
| SCHEMBL17589051 | 0.69 | MEN1 (0.37) | TDP1CYP3A4 | |
| SCHEMBL20496665 | 0.69 | MEN1 (0.37) | TDP1CYP3A4 | |
| SCHEMBL13754074 | 0.68 | ALDH1A1 (0.43) | TDP1L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10824109 | 0.68 | LMNA (0.37) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4050986 | 0.68 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL13754069 | 0.68 | ALDH1A1 (0.48) | L3MBTL1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314246-B2 | Catalytic reactions involving alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-11-20 | — | — | US | disclosed |
| US-20090216025-A1 | Catalytic reactions involving alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-08-27 | — | — | US | disclosed |
| WO-2007027752-A1 | CATALYTIC REACTIONS INVOLVING ALKENES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216025-A1 | Catalytic reactions involving alkenes | ADH5, ADH1C, ADH1A | ATM 3419/4885TDP1 3484/4885L3MBTL1 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.