Sugi Predict

Sugi Predict / Compounds / SCHEMBL531667

SCHEMBL531667

SCHEMBL531667

Fc1ccc(CCl)c(Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.43
▸ HSD17B10 Q99714 3/20 0.43
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ ALOX15 P16050 2/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ SMN1; SMN2 Q16637 5/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ CYP2C19 P33261 2/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ POLB P06746 1/20 0.41
▸ P2RX7 Q99572 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2790208 0.83 AHR (0.39) ALDH1A1RAB9AKMT2AMEN1CYP3A4
SCHEMBL18263307 0.82 ALDH1A1 (0.41) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL2370502 0.81 SLC6A4 (0.40) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL8290760 0.81 ALDH1A1 (0.42) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL13647058 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL2351920 0.79 IDO1 (0.61) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL2764669 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL211919 0.79 PNMT (0.48) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL2089246 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1
SCHEMBL697564 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10L3MBTL1ALOX15NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116730850-B Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline 山东百启生物医药有限公司 2025-05-27 — — CN claimed
CN-116730850-A Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline 山东百启生物医药有限公司 2023-09-12 — — CN claimed
CN-114369082-B Pyridine substituted spiro compounds and application thereof in preparation of anti-plant virus agent 贵州大学 2023-09-05 — — CN claimed
CN-114369082-A Pyridine substituted spiro compound, preparation method thereof and application thereof in preparation of anti-plant virus medicament 贵州大学 2022-04-19 — — CN claimed
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 — — WO claimed
US-12435078-B2 Pyridazinones and methods of use thereof GFB (ABC), LLC (US) 2025-10-07 — — US disclosed
CN-116730850-B Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline 山东百启生物医药有限公司 2025-05-27 — — CN disclosed
CN-114029091-B Dual ligand catalytic system for ethylene selective trimerization, preparation method and application thereof 浙江智英石化技术有限公司 2024-01-16 — — CN disclosed
CN-116730850-A Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline 山东百启生物医药有限公司 2023-09-12 — — CN disclosed
CN-116730850-A Preparation method of 4- [ (2-chloro-4-fluorophenyl) methoxy ] -aniline 山东百启生物医药有限公司 2023-09-12 — — CN disclosed
CN-114369082-B Pyridine substituted spiro compounds and application thereof in preparation of anti-plant virus agent 贵州大学 2023-09-05 — — CN disclosed
CN-111655678-B Apoptosis signal regulating kinase-1 inhibitor and application thereof 广州市恒诺康医药科技有限公司 2023-08-22 — — CN disclosed
WO-2003048155-A1 THROMBIN INHIBITORS UNIVERSITY OF LJUBLJANA (SI) 2003-06-12 — — WO disclosed
US-20030105098-A1 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines AVENTISUB II INC. 2003-06-05 — — US disclosed
US-6479487-B1 INHIBIT CYCLIN DEPENDENT KINASES, PARTICULARLY CDK-2; ANTIAPOPTOSIS AGENT; INHIBITS DEVELOPMENT OF NEOPLASMS AVENTIS PHARMACEUTICALS INC. 2002-11-12 — — US disclosed
CN-1292789-A 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines AWANDIS PHARMACEUTICAL CORP (US) 2001-04-25 — — CN disclosed
EP-1056744-A1 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES Aventis Pharmaceuticals Inc. (US) 2000-12-06 — — EP disclosed
WO-1999043675-A1 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES AVENTIS PHARMACEUTICALS INC. (US) 1999-09-02 — — WO disclosed
US-5013354-A Tetrahydrophthalimido group, herbicides BASF AKTIENGESELLSCHAFT (DE) 1991-05-07 — — US disclosed
WO-1987007602-A2 N-(5-SUBSTITUTED METHYLENE) PHENYL HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1987-12-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105098-A1 6,9-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines CDK6, CDK5, CDK2 ALDH1A1 2147/4885HSD17B10 4297/4885L3MBTL1 1139/4885
US-12435078-B2 Pyridazinones and methods of use thereof PDXK, ATP6V1B1, REN ALDH1A1 649/4885HSD17B10 1433/4885L3MBTL1 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.