Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30303054 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL2773091 | 0.84 | RPS6KA3 (0.41) | SMN1; SMN2MAPK14 | |
| SCHEMBL29673153 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL4098463 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL29857805 | 0.82 | HTR2A (0.39) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL810490 | 0.82 | HTR2A (0.39) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL27565478 | 0.79 | CA2 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL531667 | 0.79 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8290760 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL31085527 | 0.78 | IDO1 (0.40) | ALDH1A1CYP1A2KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | claimed |
| EP-3102034-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC Foundation For Research Development (US) | 2016-12-14 | — | — | EP | claimed |
| WO-2015120281-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2015-08-13 | — | — | WO | claimed |
| EP-4748839-A1 | POLYCYCLIC COMPOUND AND USE THEREOF | CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. (CN) | 2026-05-27 | — | — | EP | disclosed |
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| US-20250136584-A1 | Benzimidazole Or Azabenzimidazole Compound, Preparation Method Therefor And Use Thereof | CHENGDU DI'AO JIUHONG PHARMACEUTICAL FACTORY (CN) | 2025-05-01 | — | — | US | disclosed |
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| CN-119137105-A | GPR35 modulators and uses thereof | 交信医药研发公司 | 2024-12-13 | — | — | CN | disclosed |
| EP-4467538-A1 | BENZIMIDAZOLE OR AZABENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Di'Ao Jiuhong Pharmaceutical Factory (CN) | 2024-11-27 | — | — | EP | disclosed |
| EP-0995742-A1 | SULFONAMIDE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-26 | — | — | EP | disclosed |
| EP-0882720-A1 | METHODS FOR MODIFYING 1,3,5-TRIAZINE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5792867-A | Method of alkylating of triazine derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0711760-A1 | METHOD OF ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0212428-B1 | DIHYDROBENZO/B /THIOPHENES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS ANTIFUNGALS | SCHERING CORPORATION (US) | 1990-06-06 | — | — | EP | disclosed |
| US-4731364-A | Dihydrobenzo(B)thiophenes and pharmaceutical compositions thereof useful as antifungals | SCHERING CORPORATION (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0212428-A1 | Dihydrobenzo/b /thiophenes and pharmaceutical compositions thereof useful as antifungals | SCHERING CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| EP-0060617-A1 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, GLP1R | ALDH1A1 4357/4885CYP1A2 1241/4885CYP2C19 795/4885 |
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | ALDH1A1 198/4885CYP1A2 227/4885CYP2C19 476/4885 |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, FFAR3 | ALDH1A1 3776/4885CYP1A2 1343/4885CYP2C19 1106/4885 |
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | GPR35, GPR34, GPR68 | ALDH1A1 2672/4885CYP1A2 3542/4885CYP2C19 3760/4885 |
| US-20250136584-A1 | Benzimidazole Or Azabenzimidazole Compound, Preparation Method Therefor And Use Thereof | GLP1R, GIPR, SLC5A1 | ALDH1A1 608/4885CYP1A2 1798/4885CYP2C19 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.