SCHEMBL531777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531650	0.86	XDH (0.40)	VCAM1XDHALDH5A1ABATALDH1A1
	SCHEMBL531735	0.85	TUBB4A (0.44)	XDHALDH1A1MAPTPOLBLMNA
	SCHEMBL532854	0.85	XDH (0.43)	VCAM1XDHALDH5A1ABATALDH1A1
	SCHEMBL19358667	0.79	VCAM1 (0.54)	VCAM1XDHALDH5A1ABATALDH1A1
	SCHEMBL31576683	0.78	MAPT (0.56)	ALDH1A1MAPTKMT2APOLBMEN1
	SCHEMBL5350350	0.78	ALDH5A1 (0.48)	VCAM1ALDH5A1ABATALDH1A1MAPT
	SCHEMBL531886	0.78	ALDH5A1 (0.48)	VCAM1ALDH5A1ABATALDH1A1MAPT
	SCHEMBL532738	0.76	ALDH1A1 (0.42)	ALDH1A1MAPTKMT2AMEN1MAPK1
	SCHEMBL531788	0.75	ALDH1A1 (0.49)	VCAM1ALDH5A1ABATALDH1A1MAPT
	SCHEMBL18305024	0.75	ALDH1A1 (0.38)	ALDH1A1MAPTKMT2APOLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.