SCHEMBL532854

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531650	0.86	XDH (0.40)	XDHALDH5A1ABATALDH1A1VCAM1
	SCHEMBL531777	0.85	VCAM1 (0.43)	XDHALDH5A1ABATALDH1A1VCAM1
	SCHEMBL531735	0.85	TUBB4A (0.44)	XDHALDH1A1KDM4ECYP3A4MAPT
	SCHEMBL30806384	0.85	KMT2A (0.42)	ALDH1A1SRD5A2TPMTKMT2A
	SCHEMBL28082066	0.85	KMT2A (0.42)	ALDH1A1SRD5A2TPMTKMT2A
	SCHEMBL30806393	0.85	KMT2A (0.42)	ALDH1A1SRD5A2TPMTKMT2A
	SCHEMBL28082067	0.85	KMT2A (0.42)	ALDH1A1SRD5A2TPMTKMT2A
	SCHEMBL28529013	0.82	ALDH1A1 (0.38)	ALDH1A1SRD5A2MAPTTPMTKMT2A
	SCHEMBL18305024	0.82	ALDH1A1 (0.38)	ALDH1A1SRD5A2KDM4EMAPTTPMT
	SCHEMBL28533883	0.82	ALDH1A1 (0.38)	ALDH1A1SRD5A2KDM4EMAPTTPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.