Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325380 | 0.90 | ANPEP (0.40) | SOAT1 | |
| SCHEMBL5317625 | 0.90 | MMP1 (0.34) | ALDH1A1OPRM1OPRD1SLC6A2SLC6A4 | |
| SCHEMBL5368861 | 0.89 | CETP (0.31) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5316333 | 0.88 | ADAM17 (0.38) | ALDH1A1KDM4EOPRK1ADRB1SLC6A2 | |
| SCHEMBL5395845 | 0.87 | MMP1 (0.35) | ALDH1A1KDM4EOPRM1OPRD1 | |
| SCHEMBL5316662 | 0.86 | MTNR1B (0.37) | OPRM1OPRK1SLC6A2SLC6A4BACE1 | |
| SCHEMBL5322497 | 0.82 | SLC6A2 (0.36) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5318795 | 0.81 | MMP2 (0.38) | — | |
| SCHEMBL5419543 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ESLC6A4SLC6A3 | |
| SCHEMBL5373840 | 0.80 | MMP2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |