Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321171 | 0.90 | HTT (0.44) | RAB9AALDH1A1KDM4EATMTACR1 | |
| SCHEMBL5322144 | 0.86 | LMNA (0.47) | HPGDALDH1A1KMT2AMEN1TACR1 | |
| SCHEMBL8605476 | 0.81 | CHRNB2 (0.53) | TDP1NPC1HTR2AALDH1A1KDM4E | |
| SCHEMBL14017766 | 0.80 | ADRA2B (0.50) | TDP1NPC1RAB9AOPRK1ADRA2B | |
| SCHEMBL13452589 | 0.80 | ADRA2B (0.50) | TDP1NPC1RAB9AOPRK1ADRA2B | |
| SCHEMBL5164752 | 0.77 | HTR2A (0.47) | NPC1RAB9AOPRK1ADRA2BADRA2C | |
| SCHEMBL19729281 | 0.75 | ALDH1A1 (0.42) | HTR2AALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL27601264 | 0.75 | NR4A2 (0.53) | TDP1NPC1RAB9AOPRK1ADRA2B | |
| SCHEMBL890170 | 0.73 | KMT2A (0.56) | NPC1RAB9AOPRK1ADRA2BADRA2C | |
| SCHEMBL9267301 | 0.73 | KMT2A (0.56) | NPC1RAB9AOPRK1ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204652-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001009110-A1 | NOVEL SUCCINATE DERIVATIVE COMPOUNDS USEFUL AS CYSTEINE PROTEASE INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-08 | — | — | WO | disclosed |