Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322150 | 0.83 | KDM4E (0.38) | DRD2HTR1ADRD3 | |
| SCHEMBL5325651 | 0.83 | LMNA (0.47) | — | |
| SCHEMBL5285665 | 0.82 | HSD17B10 (0.35) | — | |
| SCHEMBL5325599 | 0.82 | KDM4E (0.38) | — | |
| SCHEMBL14622410 | 0.81 | MAPT (0.43) | — | |
| SCHEMBL5321659 | 0.80 | ALOX15 (0.43) | KCNH2 | |
| SCHEMBL5323186 | 0.79 | MAPT (0.51) | HTR1A | |
| SCHEMBL5321578 | 0.76 | PTGS2 (0.37) | — | |
| SCHEMBL5323252 | 0.75 | PTGS2 (0.35) | — | |
| SCHEMBL5327487 | 0.73 | DNM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |