SCHEMBL5326210

SCHEMBL5326210

CC1(C)CC(CCCCNc2ncnc(N(CCCCCCNC3CC(C)(C)NC(C)(C)C3)C3CC(C)(C)NC(C)(C)C3)n2)CC(C)(C)N1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.36
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7736032 0.94 SLC2A1 (0.33) SLC2A1
SCHEMBL29990431 0.87 SLC2A1 (0.39) SLC2A1KDM4ELMNAGAA
SCHEMBL14775927 0.83 DNM2 (0.38) LMNA
SCHEMBL29359677 0.83 SLC2A1 (0.40) SLC2A1KDM4ELMNAGAA
SCHEMBL5555122 0.83 SLC2A1 (0.40) SLC2A1KDM4ELMNAGAA
SCHEMBL5326213 0.82 SLC2A1 (0.34) SLC2A1
SCHEMBL3952306 0.81 TSHR (0.30)
SCHEMBL13779811 0.81 SLC2A1 (0.35) SLC2A1
SCHEMBL5482577 0.81
SCHEMBL7736035 0.80 SLC2A1 (0.32) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391949-B1 None US claimed
US-6800676-B2 ULTRAVIOLET RADIATION ABSORBERS; HEAT AND OXIDATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2004-10-05 US claimed
US-6638997-B2 Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-28 US claimed
US-6586507-B2 For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-01 US claimed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US claimed
US-20030004235-A1 Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORP. 2003-01-02 US claimed
US-6489383-B1 SUCH AS 2-(2-HYDROXY-3-(1,1-DI(4-2-(BROMOETHOXY)PHENYL) ETHYL)-5-TERT-BUTYLPHENYL)-2H-BENZOTRIAZOLE FOR USE AS STOVING LACQUER, FINISHING ENAMEL FOR AUTOMOBILES CIBA SPECIALTY CHEMICALS CORPORATION 2002-12-03 US claimed
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith WOOD MERVIN G (US) 2002-11-14 US claimed
US-6451887-B1 Benzotriazoles containing α-cumyl groups substituted by heteroatoms and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2002-09-17 US claimed
US-6420463-B1 HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORP. 2002-07-16 US claimed
US-6403681-B2 STABILIZER FOR PLASTICS CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-11 US claimed
US-6391949-B2 FOR AUTOMOBILE FINISHES; HEAT, OXIDATION, RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-21 US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US claimed
US-6376584-B1 OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-23 US claimed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
US-6391949-B1 None US disclosed
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-23 US disclosed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 SLC2A1 3532/4885KDM4E 1548/4885LMNA 764/4885
US-20020169239-A1 2H-benzotriazole UV absorbers substituted with 1,1-diphenylakyl groups and compositions stabilized therewith SUV39H1, SUV39H2, PAH SLC2A1 1646/4885KDM4E 175/4885LMNA 3381/4885
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH SLC2A1 3273/4885KDM4E 678/4885LMNA 507/4885
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 SLC2A1 3532/4885KDM4E 1548/4885LMNA 764/4885
US-20030004235-A1 Benzotriazoles containing phenyl groups substituted by heteroatoms and compositions stabilized therewith SUV39H1, SUV39H2, TPST2 SLC2A1 2226/4885KDM4E 343/4885LMNA 2979/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 SLC2A1 3780/4885KDM4E 679/4885LMNA 419/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 SLC2A1 3532/4885KDM4E 1548/4885LMNA 764/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 SLC2A1 3532/4885KDM4E 1548/4885LMNA 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.