SCHEMBL532631

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8312487	0.85	KCNQ3 (0.56)	KCNQ3KCNQ2KCNE1KCNQ1SMN1; SMN2
	SCHEMBL13485779	0.83	HDAC6 (0.58)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL4161973	0.82	MEN1 (0.61)	TAS1R3TAS1R2NPC1RAB9AMEN1
	SCHEMBL531941	0.82	CES2 (0.59)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL30147734	0.82	CES2 (0.59)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL25397315	0.81	ALDH1A1 (0.60)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL29843574	0.81	ALDH1A1 (0.60)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL532006	0.81	TAS1R3 (0.51)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL531992	0.81	SMN1; SMN2 (0.57)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2
	SCHEMBL27898401	0.80	ALDH1A1 (0.50)	TAS1R3TAS1R1TAS1R2KCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.