Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324677 | 0.86 | RGS4 (0.46) | LMNANPC1RAB9AMAPK1KMT2A | |
| SCHEMBL5323331 | 0.84 | RGS4 (0.48) | LMNASMN1; SMN2KDM4ERAB9AALDH1A1 | |
| SCHEMBL14622453 | 0.83 | CYP11B1 (0.43) | LMNAKDM4ENPC1RAB9AMAPK1 | |
| SCHEMBL5325289 | 0.83 | HSP90AA1 (0.38) | LMNANPC1RAB9AMAPK1MAPT | |
| SCHEMBL14624165 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5325697 | 0.80 | RAD51 (0.40) | LMNASMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL5323186 | 0.79 | MAPT (0.51) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5331474 | 0.79 | PTGS2 (0.38) | LMNASMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL5328955 | 0.78 | TP53 (0.49) | KMT2AMAPT | |
| SCHEMBL14624160 | 0.76 | HTT (0.35) | LMNASMN1; SMN2NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |