Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CD74 | P04233 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323331 | 0.89 | RGS4 (0.48) | TP53POLBMAPT | |
| SCHEMBL5324677 | 0.81 | RGS4 (0.46) | KMT2A | |
| SCHEMBL5325697 | 0.79 | RAD51 (0.40) | THRB | |
| SCHEMBL5325289 | 0.78 | HSP90AA1 (0.38) | TP53POLBMAPT | |
| SCHEMBL14622453 | 0.78 | CYP11B1 (0.43) | POLB | |
| SCHEMBL5331474 | 0.78 | PTGS2 (0.38) | KMT2AMAPTTHRB | |
| SCHEMBL5326762 | 0.78 | LMNA (0.49) | KMT2AMAPT | |
| SCHEMBL5326415 | 0.78 | NPBWR1 (0.39) | TP53POLBCMA1 | |
| SCHEMBL14622895 | 0.77 | PTGS2 (0.41) | POLBKMT2AMAPT | |
| SCHEMBL5330439 | 0.77 | LMNA (0.44) | TP53KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |