Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328955 | 0.89 | TP53 (0.49) | MAPTTP53POLB | |
| SCHEMBL5324677 | 0.88 | RGS4 (0.46) | RGS4LMNARAB9A | |
| SCHEMBL5325289 | 0.85 | HSP90AA1 (0.38) | RGS4MAPTTP53LMNARAB9A | |
| SCHEMBL14622453 | 0.85 | CYP11B1 (0.43) | RGS4KDM4ELMNAHTTRAB9A | |
| SCHEMBL5326762 | 0.84 | LMNA (0.49) | KDM4EMAPTLMNARAB9ASMN1; SMN2 | |
| SCHEMBL18931688 | 0.83 | RGS4 (0.53) | RGS4KDM4EMAPTLMNAHTT | |
| SCHEMBL14622465 | 0.82 | DNM1 (0.44) | KDM4EMAPTTP53PSMD14ALDH1A1 | |
| SCHEMBL14624165 | 0.82 | LMNA (0.37) | RGS4KDM4EMAPTTP53LMNA | |
| SCHEMBL5325697 | 0.81 | RAD51 (0.40) | LMNAHTTRAB9ASMN1; SMN2 | |
| SCHEMBL5288747 | 0.81 | PTGS2 (0.38) | KDM4EMAPTTP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |