Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RGS4 | P49798 | 4/20 | 0.46 |
| ▸ | RGS8 | P57771 | 4/20 | 0.46 |
| ▸ | RGS16 | O15492 | 1/20 | 0.46 |
| ▸ | RGS19 | P49795 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325289 | 0.89 | HSP90AA1 (0.38) | RGS4RGS8NPC1LMNATSHR | |
| SCHEMBL5323331 | 0.88 | RGS4 (0.48) | RGS4LMNARAB9A | |
| SCHEMBL14622453 | 0.87 | CYP11B1 (0.43) | RGS4RGS8NPC1LMNATSHR | |
| SCHEMBL5326762 | 0.86 | LMNA (0.49) | NPC1LMNAMAPK1RAB9AKMT2A | |
| SCHEMBL14624165 | 0.83 | LMNA (0.37) | RGS4RGS8NPC1LMNATSHR | |
| SCHEMBL5325697 | 0.83 | RAD51 (0.40) | NPC1LMNATSHRMAPK1RAB9A | |
| SCHEMBL5331474 | 0.82 | PTGS2 (0.38) | LMNAKMT2APTGS1PTGS2MEN1 | |
| SCHEMBL5328955 | 0.81 | TP53 (0.49) | KMT2A | |
| SCHEMBL5281280 | 0.81 | PTGS2 (0.39) | PTGS1PTGS2 | |
| SCHEMBL14624160 | 0.79 | HTT (0.35) | NPC1LMNATSHRMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |