Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337329 | 0.92 | DRD2 (0.44) | HTR6DRD2DRD4DRD3POLB | |
| SCHEMBL5335447 | 0.91 | DRD2 (0.50) | HTR6DRD2DRD4DRD3POLB | |
| SCHEMBL5335619 | 0.89 | MAPT (0.45) | HTR6DRD2DRD4DRD3POLB | |
| SCHEMBL5333246 | 0.88 | POLB (0.45) | HTR6DRD2DRD4DRD3POLB | |
| SCHEMBL5336199 | 0.86 | HTR6 (0.50) | HTR6DRD2DRD4DRD3POLB | |
| SCHEMBL5332975 | 0.86 | HTR6 (0.50) | HTR6POLBALDH1A1MEN1KMT2A | |
| SCHEMBL5327792 | 0.86 | HTR6 (0.52) | HTR6DRD2DRD4DRD3MPO | |
| SCHEMBL5336272 | 0.85 | HSD17B10 (0.45) | HTR6POLBALDH1A1KMT2AKDM4E | |
| SCHEMBL5331983 | 0.84 | HTR6 (0.52) | HTR6MPOALDH1A1KMT2ACYP3A4 | |
| SCHEMBL5335199 | 0.84 | HTR6 (0.46) | HTR6POLBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |