Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345269 | 0.82 | CSF1R (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL5322845 | 0.76 | CSF1R (0.55) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL324010 | 0.75 | KMT2A (0.49) | CYP3A4MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL38652062 | 0.75 | KMT2A (0.49) | CYP3A4MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL1104760 | 0.71 | KDM4E (0.56) | MAPK14CYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL38652180 | 0.71 | KDM4E (0.56) | MAPK14CYP3A4MEN1KMT2ANPC1 | |
| SCHEMBL9278020 | 0.69 | TP53 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL27842064 | 0.68 | HTR1A (0.50) | NPC1RAB9AS1PR5 | |
| SCHEMBL415795 | 0.68 | LTA4H (0.34) | MAPK14LTA4HMEN1KMT2ANPC1 | |
| SCHEMBL24164338 | 0.67 | YTHDC1 (0.45) | KMT2AKDM4EATMP2RX7MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002325-A1 | PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | PLEXXIKON, INC. (US) | 2007-01-04 | — | — | WO | disclosed |