Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329856 | 0.89 | DNM1 (0.45) | DNM1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL14622465 | 0.88 | DNM1 (0.44) | DNM1MAPTTP53GAAPIK3CG | |
| SCHEMBL5328796 | 0.84 | DNM1 (0.45) | DNM1ADRA2AMAPTTP53POLB | |
| SCHEMBL5325289 | 0.83 | HSP90AA1 (0.38) | MAPTTP53POLBGAAIDH1 | |
| SCHEMBL5321578 | 0.80 | PTGS2 (0.37) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL5329851 | 0.79 | KDM4E (0.43) | DNM1GAAKDM4EMEN1ALDH1A1 | |
| SCHEMBL5323252 | 0.79 | PTGS2 (0.35) | MAPTLMNASMN1; SMN2NPC1 | |
| SCHEMBL5322868 | 0.79 | ALDH1A1 (0.39) | DNM1MAPTTP53GAAKDM4E | |
| SCHEMBL5327487 | 0.77 | DNM1 (0.34) | DNM1MAPTGAALMNASMN1; SMN2 | |
| SCHEMBL14622407 | 0.75 | PTGS2 (0.38) | MAPTGAAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |