Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14622465 | 0.89 | DNM1 (0.44) | ALDH1A1MAPTKMT2AKDM4EDNM1 | |
| SCHEMBL5329856 | 0.82 | DNM1 (0.45) | ALDH1A1KMT2AKDM4ESMN1; SMN2DNM1 | |
| SCHEMBL5328787 | 0.79 | DNM1 (0.44) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5321578 | 0.78 | PTGS2 (0.37) | MAPTSMN1; SMN2APLNRLMNACYP2C9 | |
| SCHEMBL5323252 | 0.77 | PTGS2 (0.35) | MAPTSMN1; SMN2APLNRLMNACYP2C9 | |
| SCHEMBL5327487 | 0.75 | DNM1 (0.34) | MAPTSMN1; SMN2DNM1LMNACYP2C9 | |
| SCHEMBL14622407 | 0.75 | PTGS2 (0.38) | ALDH1A1MAPTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL5323331 | 0.74 | RGS4 (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2MITF | |
| SCHEMBL5325599 | 0.73 | KDM4E (0.38) | ALDH1A1MAPTKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL5325697 | 0.73 | RAD51 (0.40) | SMN1; SMN2APLNRLMNACYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |