Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329097 | 0.82 | DRD2 (0.52) | DRD2DRD4DRD3CHRNA7ALDH1A1 | |
| SCHEMBL5332148 | 0.76 | KMT2A (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL5333420 | 0.76 | MPO (0.47) | DRD2DRD4DRD3ALDH1A1HPGD | |
| SCHEMBL5333912 | 0.75 | KDM4E (0.48) | ALDH1A1HPGDKDM4EPOLBALOX15 | |
| SCHEMBL5330012 | 0.72 | HTR2A (0.49) | DRD2DRD4DRD3CHRNA7POLB | |
| SCHEMBL5331577 | 0.70 | MPO (0.48) | DRD2DRD4DRD3CHRNA7ALDH1A1 | |
| SCHEMBL5332260 | 0.70 | POLB (0.44) | DRD2DRD4DRD3CHRNA7ALDH1A1 | |
| SCHEMBL11806870 | 0.69 | HTR6 (0.57) | DRD2DRD4DRD3CHRNA7ALDH1A1 | |
| SCHEMBL5329102 | 0.69 | KDM4E (0.46) | DRD2DRD3ALDH1A1HPGDKMT2A | |
| SCHEMBL5328871 | 0.69 | DRD2 (0.47) | DRD2DRD4DRD3CHRNA7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |