Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335619 | 0.91 | MAPT (0.45) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5329261 | 0.91 | HTR6 (0.49) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5333028 | 0.87 | MPO (0.47) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5333140 | 0.87 | HTR6 (0.48) | POLBHTR6MAPTKMT2AKDM4E | |
| SCHEMBL5333246 | 0.87 | POLB (0.45) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5336199 | 0.85 | HTR6 (0.50) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5337329 | 0.82 | DRD2 (0.44) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5333822 | 0.82 | MAPT (0.45) | DRD2DRD4DRD3HTR6CHRNA7 | |
| SCHEMBL5335240 | 0.78 | ALDH1A1 (0.44) | DRD2DRD4DRD3POLBHTR6 | |
| SCHEMBL5334580 | 0.78 | ALDH1A1 (0.44) | DRD2DRD4DRD3POLBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | claimed |
| WO-2007046112-A1 | ARYLTHIOETHER TRYPTAMINE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES INC. (IN) | 2007-04-26 | — | — | WO | disclosed |