Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.65 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322929 | 0.78 | AGTR1 (0.50) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL3930136 | 0.75 | HSD17B10 (0.47) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL5315589 | 0.73 | KDM4E (0.64) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL15618087 | 0.73 | KMT2A (0.68) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL7735156 | 0.70 | KDM4E (0.74) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL5382294 | 0.69 | MAPT (0.53) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL3396642 | 0.67 | ALDH1A1 (0.37) | LMNASMN1; SMN2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11959493 | 0.66 | GPR3 (0.55) | KMT2AKDM4EGAAALDH1A1MAPT | |
| SCHEMBL29287390 | 0.66 | HSD17B10 (0.65) | KMT2ASMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL20429106 | 0.65 | MAPT (0.50) | KMT2ALMNASMN1; SMN2KDM4ERCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |