Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320985 | 0.84 | PTGS2 (0.43) | LMNASMN1; SMN2HTTCYP2C9MEN1 | |
| SCHEMBL5296183 | 0.83 | POLB (0.34) | LMNASMN1; SMN2HTTCYP2C9MEN1 | |
| SCHEMBL5324453 | 0.82 | CSF1R (0.40) | LMNAHTTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5325697 | 0.81 | RAD51 (0.40) | LMNASMN1; SMN2HTTCYP2C9TSHR | |
| SCHEMBL5331474 | 0.80 | PTGS2 (0.38) | LMNASMN1; SMN2HTTCYP2C9MEN1 | |
| SCHEMBL5330480 | 0.79 | THRB (0.36) | LMNASMN1; SMN2HTTCYP2C9 | |
| SCHEMBL5332575 | 0.79 | LMNA (0.40) | CHRM2LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL5328124 | 0.78 | PTGS2 (0.37) | SMN1; SMN2HTTCYP2C9TSHRTDP1 | |
| SCHEMBL5320843 | 0.78 | DRD2 (0.44) | LMNASMN1; SMN2HTTHPGDALDH1A1 | |
| SCHEMBL5325596 | 0.77 | MEN1 (0.41) | HTTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |