Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14622464 | 0.86 | SMN1; SMN2 (0.43) | L3MBTL1MEN1KMT2ACYP2C9HTT | |
| SCHEMBL5325571 | 0.82 | RAD51 (0.35) | CYP2C9HTT | |
| SCHEMBL5334355 | 0.82 | ADORA2B (0.33) | NR1H4L3MBTL1HTTADORA2BADORA1 | |
| SCHEMBL5325697 | 0.75 | RAD51 (0.40) | CYP2C9HTTADORA2BLMNAMAPK1 | |
| SCHEMBL5324677 | 0.75 | RGS4 (0.46) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL5331474 | 0.74 | PTGS2 (0.38) | MEN1KMT2ACYP2C9HTTADORA2B | |
| SCHEMBL14624160 | 0.73 | HTT (0.35) | CYP2C9HTTLMNAMAPK1NPC1 | |
| SCHEMBL5323331 | 0.73 | RGS4 (0.48) | HTTLMNARAB9AMAPTPOLB | |
| SCHEMBL14622453 | 0.72 | CYP11B1 (0.43) | HTTLMNAMAPK1NPC1TSHR | |
| SCHEMBL5325289 | 0.72 | HSP90AA1 (0.38) | LMNAMAPK1NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |