Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334344 | 0.82 | NR1H4 (0.32) | CYP2C9HTT | |
| SCHEMBL14622464 | 0.80 | SMN1; SMN2 (0.43) | PTGS2CYP2C9HTT | |
| SCHEMBL5325289 | 0.79 | HSP90AA1 (0.38) | RAD51HDAC6HDAC1PTGS2HDAC4 | |
| SCHEMBL5325697 | 0.76 | RAD51 (0.40) | RAD51PTGS2PTGS1CYP2C9HTT | |
| SCHEMBL5324677 | 0.76 | RGS4 (0.46) | PTGS2PTGS1 | |
| SCHEMBL5331474 | 0.75 | PTGS2 (0.38) | PTGS2PTGS1CYP2C9HTT | |
| SCHEMBL5297375 | 0.74 | MEN1 (0.42) | PTGS2CYP2C9HTT | |
| SCHEMBL5330439 | 0.74 | LMNA (0.44) | CYP2C9HTT | |
| SCHEMBL5327085 | 0.73 | PDE10A (0.42) | CYP2C9HTT | |
| SCHEMBL5326415 | 0.73 | NPBWR1 (0.39) | PTGS2CYP2C9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| WO-2007007161-A2 | NOVEL BIO-ACTIVE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |