Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.37 |
| ▸ | CTSK | P43235 | 11/20 | 0.37 |
| ▸ | CTSL | P07711 | 10/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449428 | 0.85 | FPR2 (0.39) | CTSSEPHX2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL27680758 | 0.78 | SLC6A4 (0.37) | EPHX2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5337780 | 0.77 | MMP8 (0.41) | EPHX2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5338202 | 0.77 | CTSS (0.36) | CTSSEPHX2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5319325 | 0.75 | CCR1 (0.34) | — | |
| SCHEMBL5317625 | 0.75 | MMP1 (0.34) | ALDH1A1POLBSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5322497 | 0.73 | SLC6A2 (0.36) | KDM4EALDH1A1POLBSLC6A4SLC6A3 | |
| SCHEMBL5395845 | 0.73 | MMP1 (0.35) | CTSSCTSKCTSLKDM4EALDH1A1 | |
| SCHEMBL5464768 | 0.73 | SCN7A (0.33) | — | |
| SCHEMBL2244309 | 0.73 | CHRM2 (0.53) | CTSSCTSKCTSLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |