Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449428 | 0.79 | FPR2 (0.39) | SLC6A4SLC6A3SLC6A2HRH3AMPD2 | |
| SCHEMBL5337780 | 0.78 | MMP8 (0.41) | SLC6A4SLC6A3SLC6A2EPHX2 | |
| SCHEMBL5474229 | 0.78 | CTSS (0.37) | SLC6A4SLC6A3SLC6A2EPHX2 | |
| SCHEMBL5338202 | 0.76 | CTSS (0.36) | SLC6A4SLC6A3SLC6A2EPHX2 | |
| SCHEMBL5337131 | 0.72 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2HRH3 | |
| SCHEMBL5412391 | 0.71 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2HRH3HSD11B1 | |
| SCHEMBL5379847 | 0.69 | MMP2 (0.41) | — | |
| SCHEMBL5337143 | 0.68 | MMP14 (0.35) | SLC6A4SLC6A3SLC6A2HRH3EPHX2 | |
| SCHEMBL5450417 | 0.68 | MMP2 (0.39) | LIPE | |
| SCHEMBL5317625 | 0.67 | MMP1 (0.34) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989106-B | N-hydroxyamide derivatives and their use | MERCK SERONO SA | 2013-12-04 | — | — | CN | claimed |
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | claimed |
| CN-1989106-B | N-hydroxyamide derivatives and their use | MERCK SERONO SA | 2013-12-04 | — | — | CN | disclosed |
| CN-1989106-A | N-hydroxyamide derivatives and their use | APPLIED RESEARCH SYSTEMS (AN) | 2007-06-27 | — | — | CN | disclosed |