Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 8/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10407445 | 0.83 | RAPGEF4 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19MCHR1 | |
| SCHEMBL3662287 | 0.80 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19MCHR1 | |
| SCHEMBL28023021 | 0.77 | KMT2A (0.43) | ALDH1A1CYP3A4CYP2C19THRBKDM4E | |
| SCHEMBL7405609 | 0.75 | TP53 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19THRB | |
| SCHEMBL18704533 | 0.75 | CA1 (0.43) | THRBKDM4EMAPTGAAMEN1 | |
| 1-Hexanol SCHEMBL8900405 | 0.74 | POLB (0.39) | ALDH1A1CYP3A4CYP2C19THRBMCHR1 | |
| SCHEMBL22056787 | 0.73 | GABRA1 (0.37) | ALDH1A1KDM4EHPGDGAAPTGES2 | |
| SCHEMBL20804882 | 0.73 | CDK1 (0.43) | ALDH1A1CYP3A4THRBMAPTGAA | |
| SCHEMBL11060404 | 0.73 | MCHR1 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19THRB | |
| SCHEMBL10688293 | 0.73 | CA2 (0.49) | ALDH1A1THRBKDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312266-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7250457-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2007-07-31 | — | — | US | disclosed |
| US-6927247-B2 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY (US) | 2005-08-09 | — | — | US | disclosed |
| EP-1521803-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | The College of William and Mary (US) | 2005-04-13 | — | — | EP | disclosed |
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2005-03-03 | — | — | US | disclosed |
| US-20040220310-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM AND MARY | 2004-11-04 | — | — | US | disclosed |
| US-6762231-B2 | MERCAPTAN-CONTAINING ALIPHATIC DIESTER UTILIZED FOR HALOGEN-CONTAINING POLYMERS, ESPECIALLY POLY(VINYL CHLORIDE); | THE COLLEGE OF WILLIAM AND MARY | 2004-07-13 | — | — | US | disclosed |
| US-6747081-B2 | FOR DISCOLORATION INHIBITON OF HALOPOLYMERS SUCH AS POLYVINYL CHLORIDE POLY(VINYLIDENE CHLORIDE), POLY(VINYL BROMIDE), POLY(VINYLIDENE BROMIDE), CHLORINATED POLY(VINYL CHLORIDE), CHLORINATED POLYETHYLENE, CHLORINATED RUBBER | THE COLLEGE OF WILLIAM AND MARY | 2004-06-08 | — | — | US | disclosed |
| WO-2003106550-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2003-12-24 | — | — | WO | disclosed |
| US-6667357-B2 | Organic thiol is an aromatic compound having at least one sulfhydryl group attached indirectly or directly to a benzene ring | THE COLLEGE OF WILLIAM AND MARY | 2003-12-23 | — | — | US | disclosed |
| US-20030220429-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-11-27 | — | — | US | disclosed |
| US-20030055141-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | COLLEGE OF WILLIAM AND MARY, THE | 2003-03-20 | — | — | US | disclosed |
| US-20020128363-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM & MARY (US) | 2002-09-12 | — | — | US | disclosed |
| US-20020115769-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | THE COLLEGE OF WILLIAM & MARY (US) | 2002-08-22 | — | — | US | disclosed |
| WO-2002048250-A2 | ORGANIC THIOL METAL-FREE STABILIZERS AND PLASTICIZERS FOR HALOGEN-CONTAINING POLYMERS | THE COLLEGE OF WILLIAM AND MARY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-4948827-A | STABILIZER FOR VINYL CHLORIDE POLYMERS, CHAIN TRANSFER AGENTS AND PEPTIZERS | SOCIETE FRANCAISE HOECHST (FR) | 1990-08-14 | — | — | US | disclosed |
| US-4948827-A | STABILIZER FOR VINYL CHLORIDE POLYMERS, CHAIN TRANSFER AGENTS AND PEPTIZERS | SOCIETE FRANCAISE HOECHST (FR) | 1990-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049307-A1 | Organic thiol metal-free stabilizers and plasticizers for halogen-containing polymers | TST, LANCL1, TTPA | ALDH1A1 203/4885CYP3A4 1505/4885CYP2C9 3269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.