Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997270 | 0.80 | MAOB (0.62) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL1555449 | 0.79 | MAOB (0.79) | MAOBMAOAPARP15PARP10 | |
| Hydrochloric Acid SCHEMBL9015457 | 0.79 | MAOB (0.61) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL27683488 | 0.79 | MAOB (0.61) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL5894373 | 0.78 | L3MBTL1 (0.44) | MAOBPPARDPPARAPPARGFFAR1 | |
| SCHEMBL176858 | 0.77 | MAOB (0.59) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL9015450 | 0.77 | MAOB (0.59) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL2989798 | 0.76 | MAOB (0.57) | MAOBMAOAPARP15PARP10MRGPRX4 | |
| SCHEMBL7128516 | 0.75 | MAOB (0.51) | MAOBMAOAPPARDPARP15PARP10 | |
| SCHEMBL6906563 | 0.75 | FFAR1 (0.49) | MAOBPPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214698-B2 | Beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-05-08 | — | — | US | disclosed |
| US-20060173061-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-08-03 | — | — | US | disclosed |
| EP-1558583-A1 | NOVEL PHENYLETHANOLAMINE DERIVATIVES AND THE USE OF THE SAME AS BETA-3-AGONISTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| US-20040127733-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-01 | — | — | US | disclosed |
| WO-2004039784-A1 | NOVEL PHENYLETHANOLAMINE DERIVATIVES AND THE USE OF THE SAME AS BETA-3-AGONISTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-13 | — | — | WO | disclosed |
| EP-0008653-B2 | N-substituted benzimidazoles, processes for their preparation and medicines containing them | C.H. BOEHRINGER SOHN (DE) | 1988-05-04 | — | — | EP | disclosed |
| US-4647563-A | ANTISPAMODIC AGENTS, MUSCLE RELAXANTS, ANTIALLERGENS HYPOTENSIVE AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1987-03-03 | — | — | US | disclosed |
| US-4581367-A | BRONCHOSPASMOLYTICS, ANTIALLERGENS, HYPOTENSIVE AGENTS | BOEHRINGER INGELHEIM KG (DE) | 1986-04-08 | — | — | US | disclosed |
| US-4378361-A | BRONCHODILATOR, MUSCLE RELAXANTS, ANTIALLERGENS, AND HYPOTENSIVE AGENT | BOEHRINGER INGELHEIM KG (DE) | 1983-03-29 | — | — | US | disclosed |
| EP-0008653-B1 | N-substituted benzimidazoles, processes for their preparation and medicines containing them | C.H. BOEHRINGER SOHN (DE) | 1982-06-16 | — | — | EP | disclosed |
| EP-0008653-A1 | N-substituted benzimidazoles, processes for their preparation and medicines containing them | C.H. BOEHRINGER SOHN (DE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173061-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | ADRB1, ADRB2, ADRA1A | MAOB 484/4885MAOA 522/4885PPARD 650/4885 |
| US-20040127733-A1 | New beta-agonists, processes for preparing them and their use as pharmaceutical compositions | ADRB1, ADRA1A, ADRA1D | MAOB 519/4885MAOA 548/4885PPARD 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.