Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445291 | 0.81 | TSHR (0.52) | KCNQ2MAPTLMNANPSR1TSHR | |
| SCHEMBL11446797 | 0.79 | ALDH1A1 (0.56) | KCNQ2LMNANPSR1TSHRP2RY1 | |
| SCHEMBL11445341 | 0.78 | TSHR (0.62) | KCNQ2LMNANPSR1TSHRALDH1A1 | |
| SCHEMBL11445874 | 0.74 | ALDH1A1 (0.64) | MAPTLMNAP2RY1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11453386 | 0.72 | RAB9A (0.53) | KCNQ2MAPTLMNANPSR1TSHR | |
| SCHEMBL11446342 | 0.71 | SMN1; SMN2 (0.59) | MAPTLMNANPSR1TSHRALDH1A1 | |
| SCHEMBL11445253 | 0.71 | KCNQ2 (0.65) | KCNQ2MAPTLMNANPSR1TSHR | |
| SCHEMBL535321 | 0.70 | L3MBTL1 (0.56) | MAPTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8938751 | 0.70 | MAPT (0.47) | MAPTTSHRP2RY1ALDH1A1GAA | |
| SCHEMBL10623856 | 0.69 | KDM4E (0.58) | MAPTALDH1A1HSD17B10SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414323-A1 | DERIVATIVES OF AMINOCYCLOBUTANE OR AMINOCYCLOBUTENE, THEIR METHOD OF PREPARATION AND THEIR USE AS MEDICAL PRODUCTS | Pierre Fabre Médicament (FR) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112597-A1 | DERIVATIVES OF AMINOCYCLOBUTANE OR AMINOCYCLOBUTENE, THEIR METHOD OF PREPARATION AND THEIR USE AS MEDICAL PRODUCTS | PIERRE FABRE MEDICAMENT (FR) | 2010-10-07 | — | — | WO | disclosed |