Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351520 | 0.78 | CYP2D6 (0.36) | CYP2D6ADRB1LMNAMEN1KMT2A | |
| SCHEMBL11299249 | 0.72 | MTNR1A (0.44) | ADRB1MEN1KMT2ACYP2C9ADRB2 | |
| SCHEMBL5351511 | 0.72 | CYP2D6 (0.73) | CYP2D6ADRB1LMNAMEN1KMT2A | |
| SCHEMBL5852432 | 0.72 | CYP2D6 (0.73) | CYP2D6ADRB1LMNAMEN1KMT2A | |
| SCHEMBL5347405 | 0.67 | ESR1 (0.48) | KMT2ABLMTMEM97SIGMAR1RAB9A | |
| SCHEMBL14484198 | 0.67 | MEN1 (0.46) | CYP2D6ADRB1LMNAMEN1KMT2A | |
| SCHEMBL10528219 | 0.66 | ADRB1 (0.47) | CYP2D6ADRB1LMNAMEN1KMT2A | |
| SCHEMBL17055318 | 0.65 | CA1 (0.52) | CYP2D6ADRB1LMNACYP1A2ADRB2 | |
| SCHEMBL10613421 | 0.65 | CYP2D6 (0.38) | CYP2D6KMT2AGAAMTNR1AMTNR1B | |
| SCHEMBL574859 | 0.64 | TAAR1 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | claimed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | claimed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-7227039-B2 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-06-05 | — | — | US | disclosed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | disclosed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | disclosed |
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094903-A1 | RS 1-{4-[2-(allyloxy)-ethyl]phenoxy}-3-isopropylamino propan-2-ol, process for preparation thereof and process for preparation of RS betaxolol | ADRB1, ADRB2, ADRA1A | CYP2D6 521/4885ADRB1 1/4885LMNA 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.