Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462523 | 0.80 | ACHE (0.52) | ACHETDP1RELACYP3A4TSHR | |
| SCHEMBL21881722 | 0.80 | ACHE (0.52) | ACHETDP1RELACYP3A4TSHR | |
| SCHEMBL354673 | 0.78 | CA1 (0.61) | ACHETDP1RELACYP3A4TSHR | |
| SCHEMBL1224845 | 0.76 | CYP2A6 (0.42) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL194091 | 0.76 | ACHE (0.48) | ACHETDP1RELACYP3A4TSHR | |
| SCHEMBL1259185 | 0.76 | NFE2L2 (0.46) | ACHETDP1ALDH1A1LMNACA1 | |
| SCHEMBL95902 | 0.76 | ACHE (0.48) | ACHETDP1RELACYP3A4TSHR | |
| SCHEMBL535420 | 0.76 | LMNA (0.42) | CYP3A4MEN1KMT2APOLBMAPT | |
| SCHEMBL2126713 | 0.76 | MEN1 (0.50) | ACHECYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL13665333 | 0.76 | ACHE (0.48) | ACHETDP1RELACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063093-B2 | Derivatives of 5-(halo)alkanoyl-6-hydroxy- benozofuran, benzothiophene, or indole; autoimmune diseases; systemic lupus erythematosis, rheumatoid arthritis, multiple sclerosis and psoriasis, transplant rejection; antiproliferative, anticarcinogenic, antidiabetic, antiinflammatory and antiulcer agents | HARVEY ANDREW J (AU) | 2011-11-22 | — | — | US | claimed |
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | HARVEY ANDREW J | 2008-09-11 | — | — | US | claimed |
| WO-2006096911-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS AND USES THEREOF | HARVEY ANDREW J (AU) | 2006-09-21 | — | — | WO | claimed |
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | claimed |
| EP-1060161-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 2000-12-20 | — | — | EP | claimed |
| WO-1999044989-A1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1999-09-10 | — | — | WO | claimed |
| CN-109666637-B | Application of Vgamma 9 Vdelta 2T and agonist thereof in treatment of hepatic fibrosis, liver cirrhosis and liver cancer | 清华大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-115073661-A | Resin composition and display device using same | 三星显示有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-114848656-A | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-108289902-B | Inhibitors of the mevalonate pathway as highly effective vaccine adjuvants | 清华大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-111225672-A | Mevalonate pathway inhibitors and pharmaceutical compositions thereof | 清华大学 | 2020-06-02 | — | — | CN | disclosed |
| US-20130116287-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-8247431-B2 | Heterocyclic hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-21 | — | — | US | disclosed |
| EP-0082817-A1 | Colour-photographic recording material | CIBA-GEIGY AG (CH) | 1983-06-29 | — | — | EP | disclosed |
| US-4286044-A | HIGH QUALITY DOT IMAGES USING MEROCYANINE DYES; PHOTOLITHOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4212672-A | CYANINE SENSITIZER DYE, SULFONIC ACID-SUBSTITUTED HETEROCYCLIC COMPOUND, POLYOXYALKYLENE OXIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-15 | — | — | US | disclosed |
| US-4147553-A | CYANINE DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4046572-A | SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JA) | 1977-09-06 | — | — | US | disclosed |
| US-3993437-A | Process for the dyeing of polyamide fibers with sulphur dyestuffs | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3980678-A | Anthraquinone disperse dyes | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116287-A1 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES | CYP4X1, CYP8B1, HPD | ACHE 1466/4885TDP1 2096/4885RELA 4222/4885 |
| US-20080221194-A1 | Novel Potassium channel Blockers and Uses Thereof | KCNAB1, KCNB1, KCNMB1 | ACHE 1270/4885TDP1 2783/4885RELA 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.