SCHEMBL354673

SCHEMBL354673

C[CH]Oc1ccc(OC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.61
CA2 P00918 3/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA12 O43570 1/20 0.61
CA14 Q9ULX7 1/20 0.61
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 3/20 0.52
KDM4E B2RXH2 2/20 0.52
TP53 P04637 2/20 0.52
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.52
ACHE P22303 1/20 0.50
CYP2A6 P11509 1/20 0.48
TDP1 Q9NUW8 3/20 0.48
MAPK1 P28482 2/20 0.48
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10637381 0.80 CA1 (0.65) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.78 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.78 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL535498 0.78 ACHE (0.50) CA1CA2CA7CA9ALDH1A1
SCHEMBL535420 0.76 LMNA (0.42) CA1CA2CA9CYP3A4LMNA
SCHEMBL1224845 0.76 CYP2A6 (0.42) CA1CA2CA9ALDH1A1KDM4E
SCHEMBL274124 0.76 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL2126713 0.76 MEN1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL96668 0.76 ALDH1A1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL1259185 0.76 NFE2L2 (0.46) CA1CA2CA7CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3172259-B1 NOVEL POLYMERS CONTAINING SULPHONAMIDE SODIUM OR LITHIUM SALTS, PRODUCTION METHODS THEREOF AND USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2021-05-19 EP claimed
CN-106754853-B Irreversible affinity labeling reagent for labeling GST and application 重庆医科大学 2020-02-04 CN claimed
CN-107004455-B New polymers, preparation method containing sulfonamide sodium or lithium salts and its purposes as cell electrolyte CDP创新公司 2019-07-16 CN claimed
US-10109883-B2 Polymers containing sulfonamide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries CPD INNOVATION (FR) 2018-10-23 US claimed
EP-2200440-B1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS CRESTONE INC (US) 2017-07-19 EP claimed
US-20170170516-A1 NOVEL POLYMERS CONTAINING SULFONAMIDE SODIUM OR LITHIUM SALTS, METHODS FOR PRODUCTION THEREOF AND USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2017-06-15 US claimed
US-8148380-B2 Antibacterial amide and sulfonamide substituted heterocyclic urea compounds CRESTONE, INC. (US) 2012-04-03 US claimed
US-20120015941-A1 Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds CRESTONE, INC. (US) 2012-01-19 US claimed
EP-2200440-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS Crestone, Inc. (US) 2010-06-30 EP claimed
WO-2009015208-A1 ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS REPLIDYNE, INC. (US) 2009-01-29 WO claimed
EP-1603880-B1 QUINOLINONE/BENZOXAZINONE DERIVATIVES AND USES THEREOF HOFFMANN LA ROCHE (CH) 2008-05-07 EP claimed
EP-0159584-B1 N-(AZOLYLCARBAMOYL)-HYDROXYL AMINES AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1989-01-18 EP claimed
US-4678798-A PLANTS, SEEDS BASF AKTIENGESELLSCHAFT (DE) 1987-07-07 US claimed
EP-0159584-A2 N-(azolylcarbamoyl)-hydroxyl amines and fungicides containing them BASF Aktiengesellschaft (DE) 1985-10-30 EP claimed
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG SHIONOGI & CO., LTD. (JP) 2024-06-06 US disclosed
US-20230117695-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2023-04-20 US disclosed
US-11492352-B2 Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2022-11-08 US disclosed
US-4487773-A ANTISEROTONINE AGENTS MEAD JOHNSON & COMPANY (US) 1984-12-11 US disclosed
US-4386091-A PSYCHOLOGICAL DISORDERS MEAD JOHNSON & COMPANY (US) 1983-05-31 US disclosed
US-4045567-A 2-Alkyl-5-thiazole-carboxylic acid derivatives in hypolipemiant compositions ROUSSEL UCLAF (FR) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492352-B2 Arenavirus growth inhibitor comprising polycyclic carbamoylpyridone derivative LUC7L2, CXCR6, RRP12 CA1 797/4885CA2 1027/4885CA7 82/4885
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG PREP, UNG, DPP4 CA1 1892/4885CA2 1644/4885CA7 748/4885
US-20120015941-A1 Antibacterial Amide and Sulfonamide Substituted Heterocyclic Urea Compounds NAAA, AADAC, RPSA CA1 3604/4885CA2 2838/4885CA7 2354/4885
US-20230117695-A1 ARENAVIRUS GROWTH INHIBITOR COMPRISING POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE CDK7, CCNA1, CCR10 CA1 1379/4885CA2 1543/4885CA7 141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.