Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363358 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTPOLBCYP2C19 | |
| SCHEMBL5359433 | 0.80 | POLB (0.37) | ALDH1A1LMNAMAPTPOLBCYP2D6 | |
| SCHEMBL5359454 | 0.76 | KDM4E (0.48) | ALDH1A1MAPTPOLBCYP2D6CYP2C19 | |
| SCHEMBL5361049 | 0.76 | LMNA (0.50) | ALDH1A1LMNAMAPTPOLBCYP2D6 | |
| SCHEMBL5360999 | 0.70 | FDPS (0.58) | ALDH1A1POLBGAANPSR1SMN1; SMN2 | |
| SCHEMBL8166890 | 0.70 | LMNA (0.44) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL7752752 | 0.70 | CYP2D6 (0.52) | ALDH1A1LMNAPOLBCYP2D6CYP2C19 | |
| SCHEMBL85721 | 0.69 | CYP2D6 (0.55) | ALDH1A1LMNACYP2D6CYP2C19CHRM2 | |
| SCHEMBL5007472 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTPOLBGAA | |
| SCHEMBL14908562 | 0.69 | TSHR (0.41) | MAPTPOLBCYP2C19GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | claimed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | claimed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | disclosed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | APOB, APOL1, NAPEPLD | ALDH1A1 3096/4885LMNA 2383/4885MAPT 1389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.