Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14064101 | 0.82 | MEN1 (0.62) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL6060892 | 0.78 | FDPS (0.60) | KMT2APKMLMNAMAPK1ALDH1A1 | |
| SCHEMBL5366533 | 0.77 | FDPS (0.59) | PKMLMNAALDH1A1POLBCYP1A2 | |
| SCHEMBL18307753 | 0.76 | FDPS (0.43) | KMT2APKMLMNAMAPK1ALDH1A1 | |
| SCHEMBL8003353 | 0.75 | HMGCR (0.47) | KMT2APKMLMNAMAPK1ALDH1A1 | |
| SCHEMBL5363346 | 0.73 | ALDH1A1 (0.44) | KMT2AALDH1A1POLBNPSR1MEN1 | |
| SCHEMBL578225 | 0.73 | FDPS (0.45) | KMT2APKMLMNAMAPK1ALDH1A1 | |
| SCHEMBL27517905 | 0.73 | FDPS (0.50) | KMT2APKMLMNAMAPK1ALDH1A1 | |
| SCHEMBL8170743 | 0.73 | FDPS (0.61) | KMT2APKMLMNAMAPK1POLB | |
| SCHEMBL19334562 | 0.72 | CYP1A2 (0.58) | KMT2APKMALDH1A1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | claimed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | claimed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | claimed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | claimed |
| US-7208481-B2 | Aminodiphosphonate apolipoprotein E modulators | ILEX PRODUCTS, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | PHAN HIEU TRUNG (CH) | 2005-04-07 | — | — | US | disclosed |
| EP-1482897-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | Ilex Products, Inc. (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003070169-A2 | AMINODIPHOSPHONATE APOLIPOPROTEIN E MODULATORS | ILEX PRODUCTS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075317-A1 | Aminodiphosphonate apolipoprotein e modulators | APOB, APOL1, NAPEPLD | KMT2A 3444/4885PKM 2284/4885LMNA 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.