SCHEMBL5372425

SCHEMBL5372425

Cc1cc(O)n(-c2ccccc2)c(=O)c1C#N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.57
ALDH1A1 P00352 5/20 0.57
KDM4E B2RXH2 10/20 0.56
NPSR1 Q6W5P4 1/20 0.56
HSD17B10 Q99714 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
USP2 O75604 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.46
RXFP1 Q9HBX9 1/20 0.46
TSHR P16473 1/20 0.46
RAB9A P51151 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTPN1 P18031 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29096236 0.91 LMNA (0.56) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL10600048 0.88 LMNA (0.75) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL29096234 0.86 LMNA (0.60) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL29096233 0.85 ALDH1A1 (0.59) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL30664493 0.85 ALDH1A1 (0.59) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL8765255 0.85 LMNA (0.56) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL13143002 0.85 KDM4E (0.78) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL11651603 0.85 KDM4E (0.58) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL8761154 0.84 ALDH1A1 (0.58) LMNAALDH1A1KDM4ENPSR1HSD17B10
SCHEMBL11657901 0.83 KDM4E (0.49) LMNAALDH1A1KDM4ENPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US claimed
EP-1434552-A1 METHOD FOR DYEING KERATINOUS FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
WO-2003030841-A1 METHOD FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
CN-113943495-B Isoindoline pigment and preparation method thereof 江苏丽王科技股份有限公司 2023-10-27 CN disclosed
CN-113943495-A Isoindoline pigment and preparation method thereof 江苏丽王科技股份有限公司 2022-01-18 CN disclosed
US-9786847-B2 Compound for organic photoelectric device, and organic photoelectric device and image sensor including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-10 US disclosed
US-20160155954-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE AND IMAGE SENSOR INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-02 US disclosed
CN-104629401-A Bisazo disperse dye and preparation method and application thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-05-20 CN disclosed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US disclosed
US-7204857-B1 Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL S.A. (FR) 2007-04-17 US disclosed
US-20050262647-A1 Agent for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-12-01 US disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0013879-A1 Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-06 EP disclosed
US-4189427-A Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed
US-4097475-A FOR POLYESTERS AND BLENDS WITH CELLULOSE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-27 US disclosed
US-4096145-A DYES FOR RESINS AND POLYESTER TEXTILES BASF AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-4079052-A Diazopigments containing pyridine derivatives CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3957749-A WATER-INSOLUBLE MONOAZO PYRIDINE DYES CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 LMNA 459/4885ALDH1A1 83/4885KDM4E 440/4885
US-20160155954-A1 COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE, AND ORGANIC PHOTOELECTRIC DEVICE AND IMAGE SENSOR INCLUDING THE SAME PPOX, PIEZO1, CRY1 LMNA 4532/4885ALDH1A1 86/4885KDM4E 1951/4885
US-20050262647-A1 Agent for dyeing fibers containing keratin KRT18, CKAP4, KRTCAP2 LMNA 365/4885ALDH1A1 240/4885KDM4E 1076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.