Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934884 | 0.91 | POLB (0.68) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL9490579 | 0.89 | MAPT (0.53) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL10490615 | 0.89 | MAPT (0.49) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL9719343 | 0.89 | MAPT (0.52) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL11050814 | 0.86 | CES2 (0.54) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL9080792 | 0.84 | KMT2A (0.62) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL6375687 | 0.78 | MAPT (0.96) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL6374455 | 0.78 | MAPT (0.67) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL3989915 | 0.77 | MAPT (0.41) | MAPTHTTNPSR1NPC1ALDH1A1 | |
| SCHEMBL4309730 | 0.77 | ALDH1A1 (0.60) | MAPTHTTNPSR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415777-B1 | PROCESS FOR PRODUCING NUCLEOSIDE | TAKEDA PHARMACEUTICAL (JP) | 2015-07-29 | — | — | EP | disclosed |
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-8653254-B2 | Process for producing nucleoside | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2528914-A1 | FURO [3, 2 -B]PYRANE DERIVATIVES USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS | Eisai R&D Management Co., Ltd. (JP) | 2012-12-05 | — | — | EP | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-8173705-B2 | Agent for alleviating wrinkles | SHISEIDO COMPANY LTD. (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20120071646-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2415777-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | Takeda Pharmaceutical Company Limited (JP) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011094339-A1 | FURO [3, 2 -B] PYRANE DERIVATIVES USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-08-04 | — | — | WO | disclosed |
| US-20100113450-A1 | Agent for Preventing and Alleviating Wrinkles | SHISEIDO COMPANY LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2123253-A1 | WRINKLING-PREVENTING AND -MODIFYING AGENT | Shiseido Company, Ltd. (JP) | 2009-11-25 | — | — | EP | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1880711-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | MAPT 2499/4885HTT 1249/4885NPSR1 2216/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | MAPT 2324/4885HTT 2894/4885NPSR1 4560/4885 |
| US-20100113450-A1 | Agent for Preventing and Alleviating Wrinkles | GABRB1, GABRB2, GABBR1 | MAPT 2244/4885HTT 537/4885NPSR1 604/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | MAPT 2212/4885HTT 1156/4885NPSR1 2485/4885 |
| US-20120071646-A1 | PROCESS FOR PRODUCING NUCLEOSIDE | NUDT1, PNP, HPRT1 | MAPT 4776/4885HTT 3216/4885NPSR1 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.