SCHEMBL537727

SCHEMBL537727

CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC=O

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DAGLA Q9Y4D2 10/20 0.64
MGLL Q99685 1/20 0.64
CNR1 P21554 7/20 0.63
CNR2 P34972 1/20 0.62
DAGLB Q8NCG7 3/20 0.60
MEN1 O00255 1/20 0.59
NR1I2 O75469 1/20 0.59
ABHD16A O95870 1/20 0.59
LPL P06858 1/20 0.59
MAPT P10636 1/20 0.59
LIPC P11150 1/20 0.59
PNLIP P16233 1/20 0.59
ACHE P22303 1/20 0.59
FASN P49327 1/20 0.59
KMT2A Q03164 1/20 0.59
PLA2G7 Q13093 1/20 0.59
ABHD12 Q8N2K0 1/20 0.59
ABHD6 Q9BV23 1/20 0.59
LIPG Q9Y5X9 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptane SCHEMBL27962464 1.00 DAGLA (0.64) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL9267899 1.00 DAGLA (0.64) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL28745648 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL28240792 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL28360069 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL28888021 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
Water SCHEMBL28163550 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL27806391 0.99 DAGLA (0.63) DAGLAMGLLCNR1CNR2DAGLB
Methyl Alcohol SCHEMBL27962463 0.97 DAGLA (0.65) DAGLAMGLLCNR1CNR2DAGLB
SCHEMBL9269609 0.91 DAGLA (0.54) DAGLAMGLLCNR1CNR2DAGLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
CN-104736147-A Compositions and methods for weight management UNIGEN INC 2015-06-24 CN claimed
JP-4737836-B2 2011-08-03 JP claimed
JP-2003500451-A 2003-01-07 JP claimed
CN-1365284-A Dietary or pharmaceutical composition for preventing or treating hyperoxaluria VSL PHARMACEUTICAL CO LTD (IE) 2002-08-21 CN claimed
EP-1181027-A2 DIETARY OR PHARMACEUTICAL COMPOSITION FOR USE FOR THE PREVENTION OR TREATMENT OF HYPEROXALURIA VSL Pharma Limited (IE) 2002-02-27 EP claimed
WO-2000072855-A2 DIETARY OR PHARMACEUTICAL COMPOSITION FOR USE FOR THE PREVENTION OR TREATMENT OF HYPEROXALURIA VSL PHARMA LIMITED (IE) 2000-12-07 WO claimed
US-20250276066-A1 METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS GERO PTE LTD (SG) 2025-09-04 US disclosed
US-20240342096-A1 MODIFIED RELEASE COMPOSITION OF ORLISTAT AND ACARBOSE FOR THE TREATMENT OF OBESITY AND RELATED METABOLIC DISORDERS EMPROS PHARMA AB (SE) 2024-10-17 US disclosed
EP-4364743-A3 A MODIFIED RELEASE COMPOSITION OF ORLISTAT AND ACARBOSE FOR THE TREATMENT OF OBESITY AND RELATED METABOLIC DISORDERS Empros Pharma AB (SE) 2024-08-28 EP disclosed
US-12048694-B2 Coordinated metabolic reprogramming in response to productive viral infections ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2024-07-30 US disclosed
US-20240226024-A1 SYNERGISTIC EFFECTS ON WEIGHT LOSS, IMPROVED QUALITY OF LIFE AND REDUCED GASTRO-INTESTINAL SIDE EFFECTS WITH A COMPOSITION OF ORLISTAT AND ACARBOSE EMPROS PHARMA AB (SE) 2024-07-11 US disclosed
EP-4086343-A4 USE OF BIOLOGICAL ENZYME FOR PREPARING ORLISTAT INTERMEDIATE, AND PREPARATION METHOD ZEIN BIOTECHNOLOGY CO., LTD. (CN) 2024-07-03 EP disclosed
WO-2000072855-A2 DIETARY OR PHARMACEUTICAL COMPOSITION FOR USE FOR THE PREVENTION OR TREATMENT OF HYPEROXALURIA VSL PHARMA LIMITED (IE) 2000-12-07 WO disclosed
EP-1039900-A2 PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND ORLISTAT KNOLL AKTIENGESELLSCHAFT (DE) 2000-10-04 EP disclosed
WO-1999033450-A3 PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND ORLISTAT KNOLL AG (DE) 1999-09-02 WO disclosed
WO-1999033450-A2 PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND ORLISTAT KNOLL AKTIENGESELLSCHAFT (DE) 1999-07-08 WO disclosed
US-5466708-A Carbamyloxyoxetanone compounds HOFFMANN-LA ROCHE INC. (US) 1995-11-14 US disclosed
US-5376674-A Lipase inhibitors HOFFMAN-LA ROCHE INC. (US) 1994-12-27 US disclosed
US-5260310-A Oxetanone compounds and pharmaceutical compositions containing them HOFFMANN-LA ROCHE INC. (US) 1993-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048694-B2 Coordinated metabolic reprogramming in response to productive viral infections MAVS, ATF4, PC DAGLA 4165/4885MGLL 1552/4885CNR1 3791/4885
US-20240226024-A1 SYNERGISTIC EFFECTS ON WEIGHT LOSS, IMPROVED QUALITY OF LIFE AND REDUCED GASTRO-INTESTINAL SIDE EFFECTS WITH A COMPOSITION OF ORLISTAT AND ACARBOSE FABP6, SI, FABP2 DAGLA 111/4885MGLL 7/4885CNR1 1466/4885
US-20250276066-A1 METHODS, COMPOSITIONS AND COMPOUNDS FOR TREATING AGE-RELATED DISEASES AND CONDITIONS UPF1, NLN, BRCA1 DAGLA 4201/4885MGLL 2940/4885CNR1 3597/4885
US-20240342096-A1 MODIFIED RELEASE COMPOSITION OF ORLISTAT AND ACARBOSE FOR THE TREATMENT OF OBESITY AND RELATED METABOLIC DISORDERS LIPC, ACAT2, ACACB DAGLA 83/4885MGLL 11/4885CNR1 931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.