Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096023 | 0.80 | ENPP2 (0.40) | ENPP2S1PR1DDB1CRBNSDCBP | |
| SCHEMBL1023596 | 0.76 | ENPP2 (0.50) | ENPP2S1PR1PRSS1PRSS2PRSS3 | |
| SCHEMBL23901093 | 0.74 | GABRA1 (0.39) | — | |
| SCHEMBL10921320 | 0.74 | ENPP2 (0.41) | ENPP2S1PR1DDB1CRBNPRSS1 | |
| SCHEMBL13137670 | 0.74 | ALDH1A1 (0.38) | TSHRTRPA1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL17048444 | 0.71 | MAOA (0.44) | ENPP2S1PR1DDB1CRBNSDCBP | |
| SCHEMBL4619501 | 0.71 | ALDH1A1 (0.42) | TSHRRECQLTRPA1ALDH1A1 | |
| SCHEMBL95655 | 0.71 | ENPP2 (0.45) | ENPP2DDB1CRBNPRSS1PRSS2 | |
| SCHEMBL29899606 | 0.71 | ENPP2 (0.45) | ENPP2DDB1CRBNPRSS1PRSS2 | |
| SCHEMBL16139585 | 0.71 | TRPA1 (0.42) | ENPP2TSHRTRPA1ALDH1A1CYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7271197-B2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 2007-09-18 | — | — | US | disclosed |
| US-20050256201-A1 | Phenethanolamine derivatives | GLAXO GROUP LIMITED | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256201-A1 | Phenethanolamine derivatives | PNMT, PHOSPHO1, NAPEPLD | ENPP2 312/4885S1PR1 402/4885DDB1 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.