SCHEMBL5383436

SCHEMBL5383436

CC(C)(C)c1cc(O)ccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
ALOX15 P16050 4/20 0.61
TYR P14679 3/20 0.61
HSD17B10 Q99714 3/20 0.61
LMNA P02545 2/20 0.61
HTT P42858 2/20 0.61
NR1I2 O75469 1/20 0.61
CYP2C9 P11712 1/20 0.61
MIF P14174 1/20 0.61
NFE2L2 Q16236 1/20 0.61
SMN1; SMN2 Q16637 4/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
ATP2A2 P16615 1/20 0.42
ATP2A3 Q93084 1/20 0.42
GAA P10253 2/20 0.42
RECQL P46063 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9023207 0.98 ALDH1A1 (0.59) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL2965024 0.82 ALDH1A1 (0.56) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL2160202 0.78 ALDH1A1 (0.70) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL29396798 0.77 FFAR4 (0.53) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL282399 0.77 FFAR4 (0.53) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL7858673 0.76 ALDH1A1 (0.67) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL9503147 0.76 TSHR (0.43) ALDH1A1ALOX15TYRHSD17B10LMNA
E319 SCHEMBL26745 0.76 ALDH1A1 (1.00) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL30629387 0.76 ALDH1A1 (0.67) ALDH1A1ALOX15TYRHSD17B10LMNA
SCHEMBL2154357 0.76 PGR (0.50) ALDH1A1ALOX15HSD17B10CYP2C9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5984975-A COLORFAST, WASHFAST HAIR DYES L'OREAL (FR) 1999-11-16 US claimed
EP-0652742-B1 USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS OREAL (FR) 1997-08-27 EP claimed
WO-1994027564-A1 USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS L'OREAL (FR) 1994-12-08 WO claimed
EP-3820850-B1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2026-04-01 EP disclosed
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-09-23 US disclosed
CN-112638877-B Phenyl/pyridinyl-N-phenyl/pyridinyl derivatives for the treatment of RNA viral infections ABIVAX公司 2025-04-22 CN disclosed
US-20220155287-A1 SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS UNIV CALIFORNIA (US) 2022-05-19 US disclosed
EP-3820850-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-05-19 EP disclosed
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2021-04-29 US disclosed
CN-112638877-A phenyl/pyridyl-N-phenyl/pyridyl derivatives for the treatment of RNA viral infections ABIVAX公司 2021-04-09 CN disclosed
WO-2020011816-A1 PHENYL/PYRIDYL-N-PHENYL/PYRIDYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION ABIVAX (FR) 2020-01-16 WO disclosed
CN-1490318-A Nitrogen-oxygen heterocyclic compound and preparation method thereof 长春人造树脂厂股份有限公司 2004-04-21 CN disclosed
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-08 US disclosed
US-5984975-A COLORFAST, WASHFAST HAIR DYES L'OREAL (FR) 1999-11-16 US disclosed
US-5703266-A OXIDATION HAIR DYES L'OREAL (FR) 1997-12-30 US disclosed
EP-0652742-B1 USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS OREAL (FR) 1997-08-27 EP disclosed
EP-0652742-A1 USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS. OREAL (FR) 1995-05-17 EP disclosed
WO-1994027564-A1 USE OF 3-SUBSTITUTED PARA-AMINOPHENOLS FOR DYEING KERATINOUS FIBRES AND NOVEL SUBSTITUTED 3-PARA-AMINOPHENOLS L'OREAL (FR) 1994-12-08 WO disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
US-3952106-A INSECTICIDE, MITICIDE MORTON-NORWICH PRODUCTS, INC. (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040068084-A1 Azaoxa heterocyclic compound and method of preparing the same AOX1, KDM1A, BMI1 ALDH1A1 81/4885ALOX15 228/4885TYR 485/4885
US-12421206-B2 Aryl-n-aryl derivatives for treating a RNA virus infection NSUN3, CBR3, C1R ALDH1A1 3246/4885ALOX15 2957/4885TYR 1611/4885
US-20220155287-A1 SMALL MOLECULES TARGETING THE INTRINSICALLY DISORDERED STRUCTURAL ENSEMBLE OF ALPHA-SYNUCLEIN PROTECT AGAINST DIVERSE ALPHA-SYNUCLEIN MEDIATED DYSFUNCTIONS SNCA, PARK7, SYNCRIP ALDH1A1 3157/4885ALOX15 4165/4885TYR 3734/4885
US-20210122732-A1 ARYL-N-ARYL DERIVATIVES FOR TREATING A RNA VIRUS INFECTION NSUN3, CBR3, C1R ALDH1A1 3246/4885ALOX15 2957/4885TYR 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.