Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.72 |
| ▸ | CA12 | O43570 | 3/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | CA4 | P22748 | 3/20 | 0.72 |
| ▸ | CA6 | P23280 | 3/20 | 0.72 |
| ▸ | CA5A | P35218 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.72 |
| ▸ | F13A1 | P00488 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | THPO | P40225 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | CASP2 | P42575 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL763885 | 0.97 | CYP2C19 (0.74) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL9327511 | 0.95 | CYP2C19 (0.70) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL10045210 | 0.95 | CYP2C19 (0.70) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL14619485 | 0.95 | CYP2C19 (0.70) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL15139536 | 0.94 | CA12 (0.68) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL12075033 | 0.94 | CASP2 (0.72) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL29753171 | 0.94 | CASP2 (0.72) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL12085529 | 0.94 | CA12 (0.68) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL10081835 | 0.94 | CYP2C19 (0.72) | CYP1A2CYP2C19CA12CA2CA4 | |
| SCHEMBL26485 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582695-B | pharmaceutical or cosmetic composition for treating alopecia | 朱利亚尼股份公司 | 2018-01-09 | — | — | CN | claimed |
| EP-2956117-B1 | COMPOSITION FOR COSMETIC USE SUITABLE TO PRODUCE A PIGMENTATION EFFECT ON HAIR | GIULIANI SPA (IT) | 2017-07-19 | — | — | EP | claimed |
| EP-2983656-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION FOR RESISTING SKIN AGEING THROUGH AN ANTI-INFLAMMATORY ACTION | Giuliani S.p.A. (IT) | 2016-02-17 | — | — | EP | claimed |
| US-20150202132-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION FOR TREATING ALOPECIA | GIULIANI S.P.A. (IT) | 2015-07-23 | — | — | US | claimed |
| EP-2877168-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION FOR TREATING ALOPECIA | Giuliani S.p.A. (IT) | 2015-06-03 | — | — | EP | claimed |
| CN-104582695-A | Pharmaceutical or cosmetic composition for treating alopecia | GIULIANI SPA | 2015-04-29 | — | — | CN | claimed |
| WO-2014167508-A1 | COSMETIC OR PHARMACEUTICAL COMPOSITION FOR RESISTING SKIN AGEING THROUGH AN ANTI-INFLAMMATORY ACTION | GIULIANI S.P.A. (IT) | 2014-10-16 | — | — | WO | claimed |
| WO-2014016407-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION FOR TREATING ALOPECIA | GIULIANI S.P.A. (IT) | 2014-01-30 | — | — | WO | claimed |
| CN-101300004-A | Methods of treating viral infections using polyamine analogs | PATHOLOGICA LLC (US) | 2008-11-05 | — | — | CN | claimed |
| WO-2023111076-A1 | COSMETIC COMPOSITION FOR RESTRUCTURING HAIR AND IMPROVING THE APPEARANCE THEREOF | GIULIANI S.P.A. (IT) | 2023-06-22 | — | — | WO | disclosed |
| US-20220008418-A1 | Aminoquinoline Derivatives and Uses Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-13 | — | — | US | disclosed |
| EP-2822936-B1 | AMINOQUINOLINE DERIVATIVES AND USES THEREOF | MCLEAN HOSPITAL CORP (US) | 2021-09-08 | — | — | EP | disclosed |
| US-11026943-B2 | Aminoquinoline derivatives and uses thereof | THE MCLEAN HOSPITAL CORPORATION (US) | 2021-06-08 | — | — | US | disclosed |
| CN-104582695-B | pharmaceutical or cosmetic composition for treating alopecia | 朱利亚尼股份公司 | 2018-01-09 | — | — | CN | disclosed |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | BERGERON RAYMOND J (US) | 2002-04-18 | — | — | US | disclosed |
| EP-1173223-A2 | CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | Slil Biomedical Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| US-6235794-B1 | ANTICANCER AGENT | UNIVERSITY OF FLORIDA | 2001-05-22 | — | — | US | disclosed |
| WO-2000066175-A2 | CONJUGATES AS THERAPIES FOR CANCER AND PROSTATE DISEASES | SLIL BIOMEDICAL CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| US-4500452-A | NOT SUBJECT TO ENZYME DEACTIVATION | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4472304-A | CARCINOSTATIC | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220008418-A1 | Aminoquinoline Derivatives and Uses Thereof | LRRK2, NLN, AADAT | CYP1A2 2110/4885CYP2C19 2780/4885CA12 4878/4885 |
| US-20020045780-A1 | Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment | SRM, SLC7A1, CATSPER1 | CYP1A2 3146/4885CYP2C19 1807/4885CA12 3973/4885 |
| US-20150202132-A1 | PHARMACEUTICAL OR COSMETIC COMPOSITION FOR TREATING ALOPECIA | SRM, SMS, SMOX | CYP1A2 496/4885CYP2C19 1427/4885CA12 2480/4885 |
| US-11026943-B2 | Aminoquinoline derivatives and uses thereof | LRRK2, NLRP3, AADAT | CYP1A2 1619/4885CYP2C19 1998/4885CA12 4880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.